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Both women had a fatal reaction to the gel because too much medicine entered their bodies through the skin.
One woman had a seizure in her car on the way to her appointment. The other woman had a seizure and was on a ventilator (breathing machine) for 2 years before she died.
These deadly reactions were caused by high doses of the numbing medicines in the gel and applying the gel to very large areas of skin (from groin to ankle).
Also, using plastic wrap over the skin heated it, which caused nearby blood vessels to dilate and blood flow to increase.
Totally unexpected, especially for something I had generally thought of as an old, arthritis-y thing. Gotta say, that does not seem to promise sparkling writing.
Here are some tips to avoid problems when using these medications.
The cases are all examples of harm that can occur when applying too much medicine on the skin.
Even though harm does not happen often, medicines in creams, ointments, gels, sprays, and patches can enter your body just like medicines taken by mouth.
Apply creams, ointments, gels, and sprays sparingly and only on the areas needed, not all over your body.
More medicine can be absorbed from around skin areas that rub together, like under the breasts or between the buttocks. Be sure to avoid broken skin since this will also act to increase absorption.
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